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. 2023 Dec 13;11:e16659. doi: 10.7717/peerj.16659

Figure 6. CXCL10 affects the secretion of follicle-stimulating hormone and estradiol in KGN POF model cells.

Figure 6

(A) Assessment of cisplatin concentration needed to induce KGN cell; (B) silencing efficiency of CXCL10 SiRNA in KGN cells assessed using reverse transcription quantitative polymerase chain reaction (RT-qPCR); (C and D) Expression of CXCL10 in POF cell model before and after CXCL10 silencing assessed using RT-qPCR and Western blot; the concentration of DDP that was finally used was 10 μg/mL for 48 h. (E) Secretion of estradiol (E2) was detected in KGN cells before and after CXCL10 silencing. **p < 0.01, ***p < 0.001, ****p < 0.0001.