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. 2023 Nov 15;149(20):17973–17986. doi: 10.1007/s00432-023-05494-4

Table 1.

Relationship between clinicopathological parameters of AC and SCC, and HPV integration

Variable Valid HPV integration of AC Valid HPV integration of SCC
Negative Positive P-value Negative Positive P-value
No % No % No % No %
Age 0.115 0.522
 < 40 8 32.0% 17 68.0% 1 7.7% 12 92.3%
40–49 2 8.3% 22 91.7% 1 3.4% 28 96.6%
 >  = 50 3 17.6% 14 82.4% 6 11.3% 47 88.7%
Differentiation 0.144 0.026
Well 2 9.1% 20 90.9% 3 33.3% 6 66.7%
Moderately or poorly 2 40% 3 60% 5 5.8% 81 94.2%
Stage 1.000 0.273
CIS or stage 1 9 20% 36 20% 6 12.8% 41 87.2%
Stage 2 +  1 80% 4 80% 2 4.8% 40 95.2%
Type of HPV 0.881 1.000
HPV16 6 16.7% 30 83.3% 5 7.4% 63 92.6%
HPV18 4 16.7% 20 83.3% 0 0.0% 6 100%
Non-HPV16/18 1 25.0% 3 75.0% 1 5.3% 18 94.7%
Lymph metastasis 0.171 0.676
Positive 1 100% 0 0% 1 4.5% 21 95.5%
Negative 5 14.7% 29 85.3% 7 9.6% 66 90.4%