Table 3.
FNC changes in patients with schizophrenia in the meta-analysis.
| Regions | Peak MNI coordinates | Cluster size (voxels) | SDM-Z value | P value | Heterogeneity test | Egger’s test (P value) | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | Q (P value) | |||||
| Increased FNCs | ||||||||
| Right IPC/SMG/ANG | 54 | –54 | 36 | 1497 | 2.297 | <0.0001 | 23.193 (0.508) | 0.222 |
| Bilateral mPFC | –6 | 42 | 44 | 1620 | 2.118 | <0.0001 | 18.494 (0.778) | 0.870 |
| Right DLPFC | 24 | 26 | 50 | 183 | 1.579 | 0.0007 | 20.714 (0.656) | 0.095 |
| Decreased FNCs | ||||||||
| Right insula | 38 | –8 | –10 | 2354 | –3.052 | <0.0001 | 23.920 (0.466) | 0.460 |
| Left insula | –30 | 6 | 4 | 1140 | –1.767 | 0.0009 | 25.588 (0.374) | 0.104 |
| Left PCG | –58 | –8 | 40 | 963 | –2.060 | 0.0002 | 21.866 (0.587) | 0.737 |
| Right PCG | 44 | –22 | 46 | 238 | –1.746 | 0.0010 | 18.776 (0.764) | 0.592 |
| Right ITG | 46 | –64 | –12 | 206 | –1.796 | 0.0008 | 19.944 (0.700) | 0.302 |
ANG angular gyrus, DLPFC dorsolateral prefrontal cortex, FNC functional network centrality, IPC inferior parietal cortex, ITG inferior temporal gyrus, MNI Montreal Neurological Institute, mPFC medial prefrontal cortex, PCG postcentral gyrus, Q Cochran’s Q statistic, SDM seed-based d mapping, SMG supramarginal gyrus.