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. 2023 Dec 16;24:809. doi: 10.1186/s13063-023-07838-4

Table 2.

Operating characteristics of the stopping rule for feasibility

Underlying proportion without detectable DNA double-strand breaks 0.4 0.5 0.6 0.7 0.8
% of the time study stops 19.3% 44% 74.8% 92.4% 99.4%
Expected sample size 16.3 14.1 11.1 8.7 6.9