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. 2023 Dec 16;23:1243. doi: 10.1186/s12885-023-11706-4

Table 1.

Basic features of the publications included in this meta-analysis (n = 40)

Author and year Sample size Level of expression Detection methods Cut-off value Reference gene Survival outcome HR with 95%CI LCI UCI Analysis methods Follow-up (month) NOS score
Wei L 2019 64 upregulated qRT-PCR median GAPDH OS 2.56 1.2 5.47 Univariate analysis 24 8
Cui Y 2017 68 upregulated qRT-PCR median GAPDH OS 2.07 1.13 3.79 Univariate analysis 60 8
Li XM 2020 40 upregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Zhang HY 2017 36 upregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Li CL 2019 64 upregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Yang XH 2021 41 downregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Kang BJ 2021 66 downregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Zhao LJ 2021 35 upregulated qRT-PCR median GAPDH Not reported - - - - - 7
Shi JD 2019 32 upregulated qRT-PCR median GAPDH OS 2.71 0.99 7.41 Univariate analysis 60 8
Zhao SS 2020 42 upregulated qRT-PCR Not reported GAPDH OS 2.16 0.73 6.38 Univariate analysis 60 7
Wang F 2021 50 upregulated qRT-PCR mean GAPDH OS 1.79 0.67 4.8 Univariate analysis 60 8
DFS 2.03 0.97 4.27 Univariate analysis 60 8
Gao N 2020 45 upregulated qRT-PCR mean GAPDH OS 2.34 1.19 4.61 Univariate analysis 60 6
Dong Z 2020 40 upregulated qRT-PCR mean GAPDH OS 2.36 0.9 6.17 Univariate analysis 60 6
Geng H 2020 60 upregulated qRT-PCR median GAPDH OS 1.76 0.8 3.86 Univariate analysis 36 8
Liang R 2018 60 upregulated qRT-PCR mean GAPDH OS 2.33 1.23 4.40 Univariate analysis 48 8
Pang LL 2019 42 upregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Li LP 2020 36 upregulated qRT-PCR mean GAPDH OS 3.85 1.86 10.96 Univariate analysis 60 6
Chen CH 2018 120 upregulated qRT-PCR median β-actin OS 1.3 0.88 1.9 Univariate analysis 60 8
PFS 1.24 0.85 1.79 Univariate analysis 60 8
Wang RX 2020 50 upregulated qRT-PCR mean GAPDH OS 2.55 0.85 7.66 Univariate analysis 48 6
Liu SX 2019 42 upregulated qRT-PCR median GAPDH OS 2.07 1.04 4.14 Univariate analysis 60 8
Huang YS 2022 65 upregulated qRT-PCR mean GAPDH OS 2.25 1.05 4.86 Univariate analysis 60 8
Wang Y 2019 40 upregulated qRT-PCR median GAPDH OS 2.27 0.83 6.19 Univariate analysis 48 6
Wang S 2018 128 upregulated qRT-PCR mean GAPDH OS 2.1276 1.0638 4.1667 Univariate analysis 60 6
Guo LF 2018 40 upregulated qRT-PCR mean GAPDH OS - - - - - 7
Huang YF 2021 68 upregulated qRT-PCR mean GAPDH OS 4.09 1.94 8.61 Univariate analysis 48 8
Zhang NN 2021 45 upregulated qRT-PCR mean GAPDH OS 2.27 0.69 7.41 Univariate analysis 54 8
Chen XL 2020 50 upregulated qRT-PCR mean GAPDH OS 2.11 0.9 4.96 Univariate analysis 60 8
Zhang ZH 2018 99 upregulated qRT-PCR mean GAPDH OS 1.66 0.94 2.93 Univariate analysis 60 8
Ma XR 2019 24 upregulated qRT-PCR mean GAPDH OS 3.298 1.3635 7.9774 Univariate analysis 60 6
Dong YZ 2018 49 upregulated qRT-PCR median GAPDH OS 1.84 0.94 3.59 Univariate analysis 120 8
DFS 2.22 1.17 4.19 Univariate analysis 80 8
Cui HX 2018 55 upregulated qRT-PCR mean GAPDH OS 2.234 1.0334 4.8294 Univariate analysis 80 8
Han PF 2021 118 upregulated qRT-PCR mean GAPDH OS 3.71 1.67 6.94 9 60
Jin B 2018 35 upregulated qRT-PCR median GAPDH OS 1.63 0.56 4.76 Univariate analysis 60 8
Li Y 2022 30 upregulated qRT-PCR mean GAPDH Not reported - - - - - 7
Han W 2018 66 upregulated qRT-PCR mean β-actin OS 2.73 1.381 5.397 Multivariate analysis 60 9
DFS 2.641 1.394 5.002 Multivariate analysis 60 9
Zhang ZW 2021 50 upregulated qRT-PCR median GAPDH OS 2.2 0.93 5.19 Univariate analysis 120 8
Fan HJ 2021 63 upregulated qRT-PCR mean GAPDH OS 2.459 1.584 4.971 Multivariate analysis 60 9
Jin LL 2019 42 upregulated qRT-PCR median GAPDH OS 2.46 0.96 6.29 Univariate analysis 60 6
Chen ZY 2017 42 upregulated qRT-PCR median GAPDH OS 6.06 2.44 15.07 Univariate analysis 24 8
PFS 3.89 1.48 10.22 Univariate analysis 24 8
Wang XL 2020 63 upregulated qRT-PCR mean GAPDH Not reported - - - - 7