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. 2023 Dec 14;32:09636897231218408. doi: 10.1177/09636897231218408

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Efficacy of multi-lineage endometrial organoids in repairing injured endometrium. (A) Schematic diagram of intrauterine transplantation of MLEOs in endometrium-injured mice at different time points. (B) Representative H&E images of uterine sections at day 14 of injury treatment. (C) Masson trichrome-stained sections of the uterine at day 14 of injury treatment. (D) Statistical analysis of endometrial thickness after injury treatment. (E) Analysis of the number of glands. (F) Statistical analysis of fibrotic area measured in different groups. Data are the mean ± SEM. MLEO: multi-lineage endometrial organoid; H&E: hematoxylin and eosin; SEM: standard error of the mean; EEO: endometrial epithelium organoid; eMSC: endometrial mesenchymal stem cell. Student’s t test; ns, non-significant; *P < 0.05; **P < 0.01; ***P < 0.001.