Table 3.

Univariate Regression Analysis of MNV Area and Vessel Density

	MNV Area			MNV Vessel Density
	ß Coefficient	95% CI	p-value	ß Coefficient	95% CI	p-value
Sex	1.60	−1.69 to 4.89	0.332	2.88	−6.77 to 12.53	0.550
Age	0.081	0.002 to 0.16	0.045	−0.30	−0.52 to −0.08	0.009
Racial/Ethnic background	−0.43	−2.33 to 1.47	0.649	−1.31	−6.84 to 4.22	0.635
SBP	0.054	−0.28 to 0.14	0.186	−0.19	−0.43 to 0.44	0.108
DBP	0.012	−0.14 to 0.17	0.872	−0.12	−0.56 to 0.33	0.590
Smoking status	3.09	0.80 to 5.38	0.010	−4.11	−11.24 to 3.02	0.251
BMI	−0.21	−0.53 to 0.11	0.189	0.43	−0.50 to 1.36	0.355
LogMAR VA	4.75	0.28 to 9.22	0.038	−16.61	−29.31 to −3.91	0.012
Refractive Error	0.25	0.04 to 0.46	0.022	−0.68	−1.30 to −0.05	0.035
Prior PDT	−9.13	−13.94 to −4.32	<0.001	4.59	−11.61 to 20.80	0.570
Nb of prior IVIs	0.18	0.033 to 0.32	0.018	−0.29	−0.73 to 0.15	0.191
Time since last IVI	−0.035	−0.88 to 0.018	0.185	0.16	0.015 to 0.31	0.032
Active IVI Therapy	−0.30	−3.12 to 2.52	0.831	0.18	−8.02 to 8.39	0.964
IOP	0.30	−0.14 to 0.73	0.172	−0.86	−2.11 to 0.39	0.172
Lens status	0.65	−2.21 to 3.50	0.650	−0.29	−8.62 to 8.04	0.944
MNV Type	−1.47	−4.18 to 1.25	0.283	5.90	−1.91 to 13.70	0.135
MNV Pattern	−2.03	−3.61 to −0.45	0.013	6.54	2.02 to 11.07	0.006
Diagnosis (MMD vs AMD)	2.98	0.29 to 5.67	0.031	−8.57	−16.41 to −0.73	0.033

Note: Significant p-values (<0.05) are highlighted in bold.

Abbreviations: MNV, macular neovascularization; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body-mass index; VA, visual acuity; PDT, photodynamic therapy; IVI, intravitreal injection; IOP, intraocular pressure; MMD, myopic macular degeneration; AMD, age-related macular degeneration.