Table 1.
Final liver, spleen weights, and colon assessment of mice
Group | Negative control | Positive control | 5DN treated |
---|---|---|---|
Liver Weight (mg) | 2376.34 ± 68.52 | 2262.86 ± 92.74 | 2278.04 ± 105.40 |
Spleen Weight (mg) | 236.65 ± 33.56 | 230.60 ± 30.12 | 212.78 ± 26.20 |
Colon Length (mm) | 96.82 ± 2.64a | 86.14 ± 3.72b | 95.98 ± 2.92a |
Colon W/L ratio (mg/mm) | 3.68 ± 0.30a | 4.32 ± 0.50b | 3.76 ± 0.28a |
Tumor incidence | 0a | 100% b (20/20) | 65%c (13/20) |
Tumor multiplicity | 0a | 5.70 ± 1.10b | 2.50 ± 0.50c |
Tumor burden (mm3) | 0a | 13.48 ± 2.32b | 6.69 ± 1.82c |
All values are represented as mean ± SEM. Different notations indicate statistically significant difference (p < 0.05, n=20) according to ANOVA analysis followed by Tukey’s HSD test. Tumor incidence is analyzed by Fisher’s exact probability test.