Table 3.
Adjusted means and their 95 % confidence intervals (CI) for adult echocardiography outcomes in 2011 according to the number of siblings among males.
| Outcome | Model 1 |
P for trend | n | Model 2 |
P for trend | n | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of siblings |
Number of siblings |
|||||||||||||||
| 0 |
1 |
≥2 |
0 |
1 |
≥2 |
|||||||||||
| Adjusted means | 95%CI | Adjusted means | 95%CI | Adjusted means | 95%CI | Adjusted means | 95%CI | Adjusted means | 95%CI | Adjusted means | 95%CI | |||||
| LV Mass (g/m2.7)a | 32.1 | 30.8–33.3 | 32.4 | 31.7–33.1 | 32.6 | 31.9–33.3 | 0.77 | 859 | 32.1 | 30.8–33.3 | 32.5 | 31.8–33.2 | 32.5 | 31.8–33.2 | 0.77 | 777 |
| IV septal wall (mm)a | 7.8 | 7.6–7.9 | 7.9 | 7.8–8.0 | 7.8 | 7.7–7.9 | 0.18 | 860 | 7.80 | 7.6–7.9 | 7.90 | 7.8–8.0 | 7.80 | 7.7–7.9 | 0.34 | 778 |
| LV posterior wall (mm)a | 7.8 | 7.7–8.0 | 7.8 | 7.7–7.8 | 7.7 | 7.6–7.8 | 0.13 | 859 | 7.80 | 7.6–7.9 | 7.70 | 7.6–7.8 | 7.70 | 7.6–7.8 | 0.41 | 777 |
| E/e' | 4.6 | 4.4–4.7 | 4.6 | 4.5–4.7 | 4.6 | 4.5–4.7 | 0.77 | 883 | 4.5 | 4.4–4.7 | 4.6 | 4.5–4.7 | 4.6 | 4.5–4.7 | 0.56 | 793 |
| E/Aa | 1.4 | 1.3–1.5 | 1.5 | 1.5–1.5 | 1.5 | 1.5–1.5 | 0.01 | 893 | 1.4 | 1.3–1.5 | 1.5 | 1.5–1.5 | 1.5 | 1.4–1.5 | 0.03 | 801 |
| LAVI | 23.6 | 22.4–24.8 | 23.4 | 22.7–24.1 | 23.3 | 22.6–24.0 | 0.90 | 886 | 23.2 | 21.9–24.5 | 22.9 | 22.2–23.7 | 23.0 | 22.1–23.8 | 0.93 | 801 |
| LV diameter (mm) | 54.2 | 53.3–55.0 | 54.4 | 53.9–54.8 | 54.5 | 54.0–55.0 | 0.75 | 862 | 54.0 | 53.2–54.9 | 54.3 | 53.8–54.8 | 54.5 | 54.0–55.0 | 0.68 | 779 |
| LVEF (%) | 57.3 | 56.7–57.9 | 57.7 | 57.4–58.1 | 57.8 | 57.4–58.1 | 0.36 | 891 | 57.3 | 56.7–57.9 | 57.7 | 57.3–58.0 | 57.7 | 57.3–58.1 | 0.56 | 803 |
| Cardiac output (l/min)a | 5.3 | 5.1–5.6 | 5.3 | 5.2–5.5 | 5.2 | 5.1–5.4 | 0.70 | 838 | 5.3 | 5.0–5.5 | 5.3 | 5.2–5.4 | 5.3 | 5.1–5.4 | 0.99 | 760 |
| Nb | 125 | 400 | 369 | 118 | 353 | 332 | ||||||||||
a Data skewed; logarithmic transformation was used in statistical analyses. b In model 1, N varied between 115 and 125 in participants with no siblings, 374–400 in participants with one sibling, and 348–369 in participants with two or more siblings. In model 2, N varied between 110 and 118 in participants with no siblings, 334–353 in participants with one sibling, and 315–332 in participants with two or more siblings. Adjusted Model 1 included age. Adjusted model 2 age, childhood SES (household annual income) and childhood risk factors (LDL-cholesterol, HDL-cholesterol, triglycerides, systolic blood pressure, and body mass index), adult SES (annual income) and adult risk factors (LDL-cholesterol, HDL-cholesterol, triglycerides, systolic blood pressure, body mass index, serum glucose concentration, and smoking status).