Table 4.

Adjusted means and their 95 % confidence intervals (CI) for adult vascular outcomes in 2007 or 2001 according to the number of siblings among females.

Outcome	Model 1						P for trend	n	Model 2						P for trend	n
	Number of siblings								Number of siblings
	0		1		≥2				0		1		≥2
	Adjusted means	95%CI	Adjusted means	95%CI	Adjusted means	95%CI			Adjusted means	95%CI	Adjusted means	95%CI	Adjusted means	95%CI
Carotid distensibility (%/10 mmHg)	2.0	1.9–2.1	2.1	2.0–2.1	2.1	2.0–2.1	0.81	1435	2.1	2.0–2.2	2.0	2.0–2.1	2.1	2.0–2.2	0.33	1192
Flow mediated dilation (%)	10.4	9.7–11.0	10.0	9.6–10.3	9.4	9.0–9.8	0.03	1421	10.7	10.0–11.5	10.3	9.8–10.7	9.6	9.2–10.1	0.03	1186
Pulse wave velocity (m/s)	7.8	7.6–8.0	7.6	7.5–7.8	7.8	7.7–7.9	0.08	1014	7.7	7.5–7.8	7.7	7.5–7.8	7.7	7.6–7.8	0.82	931
Intima-media thickness (μm)	641	627–656	635	627–644	633	623–642	0.60	1436	613	601–625	607	600–614	609	601–616	0.66	1192
Na	210		631		595				166		525		501

b In model 1, N varied between 143 and 210 in participants with no siblings, 435–631 in participants with one sibling, and 436–595 in participants with two or more siblings. In model 2, N varied between 124 and 166 in participants with no siblings, 401–525 in participants with one sibling, and 406–501 in participants with two or more siblings. Adjusted Model 1 included age. Adjusted model 2 age, childhood SES (household annual income) and childhood risk factors (LDL-cholesterol, HDL-cholesterol, triglycerides, systolic blood pressure, and body mass index), adult SES (annual income) and adult risk factors (LDL-cholesterol, HDL-cholesterol, triglycerides, systolic blood pressure, body mass index, serum glucose concentration, and smoking status).