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. Author manuscript; available in PMC: 2023 Dec 18.
Published in final edited form as: Cell Rep. 2023 Nov 1;42(11):113351. doi: 10.1016/j.celrep.2023.113351

Figure 3. Open chromatin patterns are independent of gene expression patterns.

Figure 3.

The classification and stratification of genes and CREs is based on their expression and accessibility patterns in four tissues (adrenal gland, artery, heart, and kidney). The x axis represents sixteen categories (columns) into which each gene is classified from the union of the top 10,000 genes across the four tissues. These categories are determined based on the expression pattern of the gene (expressed or not expressed) in the four tissues. The letters (A, adrenal; R, artery; H, heart; K, kidney) associated with each category indicate the tissues in which the genes are expressed. The y axis represents the stratification of CREs within each gene category. The CREs are further categorized based on their accessibility pattern (open or not open) across the same four tissues. The letters (A, R, H, and K) in the CRE category names indicate the tissues in which the corresponding regions are open. The numbers within each cell of the figure represent the percentage of CREs in a given CRE category relative to the total number of CREs across all categories in one gene category.