Figure 6. Specific transcription factors are differentially enriched for predicted regulatory variants.

Heatmaps showing enrichment of transcription factor (TF) motifs across four tissues in 11-mers with large SVM weights from the trained SVM models (left) and in regions overlapping predicted regulatory variants (right). Motifs were clustered based on their enrichment pattern across tissues on the left. The motifs in both heatmaps are ordered identically. Representative TF motifs enriched in the artery and heart are highlighted.