. 2023 Dec 4;66(23):15801–15822. doi: 10.1021/acs.jmedchem.3c01321

Table 3. SmBRD3(2) K_d Values (ITC) for the Carboxylic Acids 11 and 13–15 and Schistosomula Phenotype and Movement EC₅₀ Values for the Corresponding Ethyl Esters 18 and 20–22^d.

Mean value of 3 repeats ± s.e.m.

95% Confidence Interval (CI).

Mean value of 2 repeats ± s.e.m.

A color scale is used with darker purple representing lower K_d values or lower EC₅₀ values.

Table 3. SmBRD3(2) Kd Values (ITC) for the Carboxylic Acids 11 and 13–15 and Schistosomula Phenotype and Movement EC50 Values for the Corresponding Ethyl Esters 18 and 20–22d.