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. 2023 Nov;193(11):1762–1775. doi: 10.1016/j.ajpath.2023.02.002

Figure 6.

Figure 6

Western blot analysis of fibrosis markers in HCFs and HKCs in three-dimensional cell culture in response to stimulation using LH 5 mIU/mL or FSH 10 mIU/mL for 4 weeks. A: Fibronectin-containing extra domain A (EDA-Fn) expression. LH 5 mIU/mL: HCF (SEM = 0.4420) versus HKC (SEM = 0.02596); P = 0.042. HKC: control versus LH 5 mIU/mL (SEM = 0.02596); P = 0.0150. B: α–Smooth muscle actin (SMA) expression. LH 5 mIU/mL: HCF (SEM = 0.2461) versus HKC (SEM = 0.06353); P = 0.015. HKC: control versus FSH 10 mIU/mL (SEM = 0.07532); P = 0.0197. HKC: control versus LH 5 mIU/mL (SEM = 0.06353); P = 0.0084. Data are expressed as means ± SEM. ∗P < 0.05 and ∗∗P < 0.01.