Table 1.

Characteristics of patients with eosinophilic myocarditis with and without cardiac magnetic resonance (CMR) imaging at presentation

	All patients n = 27	CMR+ n = 15	CMR− n = 12	p-value
Age, y	52.0 ± 17.2	51.2 ± 16.8	53.1 ± 18.4	0.787
Sex, female, n (%)	11 (41)	6 (40)	5 (42)	1.000
Time from symptom onset to hospital admission, days	3 (1–5)	2 (1–8)	4 (2–5)	0.980
Etiology, n (%)				0.543
Hypersensitivity	10 (37)	4 (27)	6 (50)
Hypereosinophilic syndrome	7 (26)	4 (27)	3 (25)
Eosinophilic granulomatosis with polyangitis	3 (11)	2 (13)	1 (8)
Cancer	1 (4)	0	1 (8)
Infectiona	1 (4)	1 (7)	0
Undefined	5 (19)	4 (27)	1 (8)
Key laboratory findings on admission
Peripheral eosinophilia (> 0.44 × 109/L), n (%)	16 (59)	9 (60)	7 (58)	1.000
Elevated cardiac troponins, n (%)b	27 (100)	15 (100)	12 (100)	NA
Elevated natriuretic peptides, n (%)c	13/16 (81)	9/11 (82)	4/5 (80)	1.000
Electrocardiography
ST segment elevation or depression, n (%)	12 (44)	7 (47)	5 (42)	0.795
T wave inversions only, n (%)	5 (19)	3 (20)	2 (17)	1.000
Bundle branch block, n (%)	3 (11)	1 (7)	2 (17)	0.569
Atrio-ventricular block, 3rd degree, n (%)	4 (15)	3 (20)	1 (8)	0.605
Echocardiography
Left ventricular end diastolic diameter, mm, n = 25/14/11	53 ± 10	50 ± 7	58 ± 12	0.088
Interventricular septal thickness, mm, n = 15/10/5	11 (11–15)	12 (11–15)	11 (10–12)	0.286
Left ventricular ejection fraction, %	41.3 ± 17.5	48.8 ± 17.0	31.9 ± 13.5	0.008
<50%, n (%)	15 (56)	5 (33)	10 (83)	0.009
<30%, n (%)	8 (30)	1 (7)	7 (58)	0.008

Data are numbers (%) of cases, means ± standard deviation, or medians (interquartile range)

^aNon-parasitic infection

^bTroponin T > 50 ng/L or Troponin I > 125 ng/L

^cN-terminal brain natriuretic pro-peptide > 300 ng/L or brain natriuretic peptide > 100 ng/L