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. Author manuscript; available in PMC: 2023 Dec 18.
Published in final edited form as: Biomaterials. 2021 Oct 2;278:121140. doi: 10.1016/j.biomaterials.2021.121140

Fig. 2. Pharmacokinetics of POXOL and Abraxane® in rats and rhesus macaques.

Fig. 2

(A) Schematic illustration of stable isotope ultrafiltration assay (SITUA) (created with BioRender.com). Equations for free, encapsulated and protein-bound PTX time-concentration comparison for POXOL (batch 3) and Abraxane® in (B) utilized rats and (C) rhesus macaques. A two-arm parallel study design was in rats (n=7–8) and a crossover design was used in rhesus macaques (n=2) (B and C).