Study	Reason for exclusion
Achong 1997	No caries outcome reported, only bacterial counts
Araujo 2002	Split‐mouth design
Axelsson 1976	Concomitant fluoride administration
Axelsson 1987	Prophylaxis available to all groups during the experimental period. Flouride varnish and additional chlorhexidine received by some members of each group
Bratthall 1995	Split‐mouth design
Dolles 1980	Concomitant fluoride administration
Emilson 1982	Fluoride comparator
Ersin 2006	Fluoride comparator
Ersin 2008	Fluoride comparator. Only one of the interventions was considered eligible for this review, as the other comparisons were either not relevant or not considered 'routine dental care'
Fennis‐le 1998	Concomitant fluoride administration
Gisselsson 1988	Concomitant fluoride administration
Gisselsson 1994	Concomitant fluoride administration
Gisselsson 2005	Concomitant fluoride administration
Gokalp 2005	Fluoride comparator
Haukali 2003	Split‐mouth design
Hausen 2000	Concomitant fluoride administration
Holst 2001	Concomitant fluoride administration
Hoszek 1996	Split‐mouth design
Hoszek 2005	Split‐mouth design
Irmisch 2000	Split‐mouth design
Joharji 2001	Split‐mouth design
Leksell 2003	Fluoride comparator
Lindquist 2010	Concomitant fluoride administration
Neeraja 2008	Not RCT
Petersson 1997	Fluoride comparator
Petti 2006	Not RCT
Plotzitza 2005	Quote: "The allocation of children to groups CHX and C depended on the mothers voluntary participation in the 3‐month appointments for CHX applications". Non‐randomised study
Rodrigues 1999	Split‐mouth design
Spets‐Happonen 1985	Fluoride comparator
Spets‐Happonen 1991	Concomitant fluoride administration
Splieth 2000	Fluoride comparator
Zhang 2006	Split‐mouth design
Zickert 1983	Not RCT

C: control
 CHX: chlorhexidine
 RCT: randomised controlled trial