Table 1. Characteristics of the individuals studied, according to vaccination schedule, Brazil, 2021-2022.
| Variables | Not vaccinated n (%) | Two doses n (%) | Booster n (%) | p-valuea |
|---|---|---|---|---|
| Total | 402,008 (71.8) | 83,343 (14.9) | 74,515 (13.3) | |
| Year | < 0.001 | |||
| 2021 | 363,870 (86.5) | 41,866 (9.9) | 15,096 (3.6) | |
| 2022 | 38,138 (27.4) | 41,477 (29.8) | 59,419 (42.7) | |
| Sex | < 0.001 | |||
| Male | 229,599 (74.1) | 43,025 (13.9) | 37,109 (12.0) | |
| Female | 172,409 (68.9) | 40,318 (16.1) | 37,406 (15.0) | |
| Age (last birthday) | < 0.001 | |||
| 20-39 | 82,949 (84.7) | 9,719 (9.9) | 5,317 (5.4) | |
| 40-59 | 182,268 (84.5) | 20,267 (9.4) | 13,145 (6.1) | |
| 60-79 | 108,221 (62.5) | 33,983 (19.6) | 30,831 (17.8) | |
| ≥ 80 | 28,570 (39.0) | 19,374 (26.5) | 25,222 (34.5) | |
| Race/skin color | < 0.001 | |||
| White | 225,205 (70.3) | 46,956 (14.7) | 48,224 (15.1) | |
| Black | 18,305 (72.4) | 3,954 (15.6) | 3,030 (12.0) | |
| Asian | 4,482 (66.7) | 1,055 (15.7) | 1,185 (17.6) | |
| Mixed race | 153,407 (74.3) | 31,167 (15.1) | 21,984 (10.6) | |
| Indigenous | 609 (66.8) | 211 (23.1) | 92 (10.1) | |
| Brazilian macro-region | < 0.001 | |||
| Southeast | 201,303 (69.8) | 41,828 (14.5) | 45,137 (15.7) | |
| South | 88,457 (73.6) | 17,653 (14.7) | 14,154 (11.8) | |
| Midwest | 45,674 (74.2) | 9,376 (15.2) | 6,466 (10.5) | |
| North | 21,578 (83.2) | 3,131 (12.1) | 1,211 (4.7) | |
| Northeast | 44,996 (70.4) | 11,355 (17.8) | 7,547 (11.8) | |
| Risk factor | < 0.001 | |||
| None | 221,523 (77.9) | 34,871 (12.3) | 28,115 (9.9) | |
| One or more | 180,485 (65.5) | 48,472 (17.6) | 46,400 (16.9) | |
| Hospitalized in ICU b | < 0.001 | |||
| Yes | 149,618 (72.5) | 32,037 (15.5) | 24,787 (12.0) | |
| No | 252,390 (71.4) | 51,306 (14.5) | 49,728 (14.1) | |
| Respiratory support | < 0.001 | |||
| Not performed | 62,568 (59.4) | 20,436 (19.4) | 22,307 (21.2) | |
| Non-invasive | 247,270 (73.2) | 47,831 (14.2) | 42,631 (12.6) | |
| Invasive | 92,170 (78.9) | 15,076 (12.9) | 9,577 (8.2) | |
| Length of time hospitalized | < 0.001 | |||
| Mean (standard deviation) | 11.7 (12.3) | 12.1 (13.7) | 11.3 (13.2) | |
| Median (Q1;Q3) | 8.0 (4.0;14.0) | 8.0 (4.0;15.0) | 7.0 (4.0;13.0) | |
| Death | < 0.001 | |||
| No | 267,308 (69.5) | 58,878 (15.3) | 58,305 (15.2) | |
| Yes | 134,700 (76.8) | 24,465 (14.0) | 16,210 (9.2) | |
a) Pearson’s chi-square test, for the qualitative variables; and Mann-Whitney test, for the quantitative variables; b) ICU = Intensive Care Unit.