Figure 2. Risk of Incident Dementia by TG Categories.

Circles denote adjusted HRs for incident dementia, and error bars denote the corresponding 95% CIs. Adjustment was made for age, sex, race, country, smoking, alcohol consumption, education level, family history of dementia, diabetes, hypertension, waist circumference, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, statin use, other lipid-lowering medication use, and composite cognitive score at baseline and randomized aspirin in the ASPREE cohorts and adjusted for age, sex, race, smoking, alcohol consumption, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, waist circumference, systolic and diastolic blood pressure, diabetes, and medications for lipid-lowering, blood pressure-lowering, and glucose-lowering in the UK Biobank cohort. The TG values at 10th, 50th, and 90th percentile in the overall ASPREE cohort and the subcohort of participants with genotyped data were 62, 106, and 186 mg/dL and in the UK Biobank cohort were 78, 139, and 261 mg/dL. ASPREE = Aspirin in Reducing Events in the Elderly; HR = hazard ratio; TG = triglyceride.