Table 2.
List of Differentially Expressed Genes in Cases Versus Controls
| Ensembl ID | Gene name | Gene biotype | Fold change | P value | P adj |
|---|---|---|---|---|---|
| ENSG00000165949 | IFI27 | protein_coding | 5.93 | 1.32E‐09 | 6.55E‐06 |
| ENSG00000076864 | RAP1GAP | protein_coding | 4.09 | 1.48E‐06 | 6.89E‐04 |
| ENSG00000196565 | HBG2 | protein_coding | 4.00 | 4.36E‐06 | 1.20E‐03 |
| ENSG00000223609 | HBD | protein_coding | 3.43 | 2.06E‐07 | 2.36E‐04 |
| ENSG00000118520 | ARG1 | protein_coding | 3.23 | 3.82E‐09 | 1.42E‐05 |
| ENSG00000204936 | CD177 | protein_coding | 2.70 | 1.43E‐04 | 7.67E‐03 |
| ENSG00000250361 | GYPB | protein_coding | 2.69 | 1.56E‐04 | 7.92E‐03 |
| ENSG00000229314 | ORM1 | protein_coding | 2.61 | 1.64E‐06 | 7.17E‐04 |
| ENSG00000169877 | AHSP | protein_coding | 2.56 | 1.57E‐05 | 2.19E‐03 |
| ENSG00000183019 | MCEMP1 | protein_coding | 2.50 | 8.53E‐10 | 6.35E‐06 |
| ENSG00000108950 | FAM20A | protein_coding | 2.48 | 3.46E‐10 | 5.15E‐06 |
| ENSG00000204010 | IFIT1B | protein_coding | 2.36 | 5.24E‐05 | 4.40E‐03 |
| ENSG00000133742 | CA1 | protein_coding | 2.34 | 1.57E‐03 | 2.78E‐02 |
| ENSG00000112212 | TSPO2 | protein_coding | 2.31 | 4.06E‐05 | 3.78E‐03 |
| ENSG00000196517 | SLC6A9 | protein_coding | 2.30 | 4.03E‐05 | 3.78E‐03 |
| ENSG00000158578 | ALAS2 | protein_coding | 2.29 | 1.31E‐04 | 7.42E‐03 |
| ENSG00000105610 | KLF1 | protein_coding | 2.29 | 3.41E‐05 | 3.41E‐03 |
| ENSG00000118113 | MMP8 | protein_coding | 2.24 | 6.60E‐04 | 1.75E‐02 |
| ENSG00000102837 | OLFM4 | protein_coding | 2.19 | 3.49E‐03 | 4.32E‐02 |
| ENSG00000274173 | ‐ | lncRNA | 2.19 | 7.01E‐05 | 5.02E‐03 |
| ENSG00000265531 | FCGR1CP | Unprocessed pseudogene | 2.17 | 4.07E‐07 | 3.57E‐04 |
| ENSG00000257017 | HP | protein_coding | 2.17 | 8.99E‐06 | 1.67E‐03 |
| ENSG00000155659 | VSIG4 | protein_coding | 2.16 | 8.09E‐07 | 5.24E‐04 |
| ENSG00000163221 | S100A12 | protein_coding | 2.14 | 7.26E‐07 | 4.91E‐04 |
| ENSG00000163554 | SPTA1 | protein_coding | 2.14 | 5.33E‐05 | 4.40E‐03 |
| ENSG00000229391 | HLA‐DRB6 | Transcribed unprocessed pseudogene | 2.14 | 2.40E‐03 | 3.57E‐02 |
| ENSG00000156381 | ANKRD9 | protein_coding | 2.11 | 9.11E‐06 | 1.68E‐03 |
| ENSG00000179914 | ITLN1 | protein_coding | 2.09 | 1.41E‐04 | 7.61E‐03 |
| ENSG00000162873 | KLHDC8A | protein_coding | 2.06 | 2.76E‐05 | 3.09E‐03 |
| ENSG00000167768 | KRT1 | protein_coding | 2.04 | 1.35E‐03 | 2.60E‐02 |
| ENSG00000163958 | ZDHHC19 | protein_coding | 2.04 | 4.41E‐06 | 1.20E‐03 |
| ENSG00000146122 | DAAM2 | protein_coding | 2.03 | 1.72E‐03 | 2.93E‐02 |
| ENSG00000104892 | KLC3 | protein_coding | 2.01 | 3.25E‐04 | 1.25E‐02 |
| ENSG00000124469 | CEACAM8 | protein_coding | 2.01 | 4.69E‐03 | 5.12E‐02 |
| ENSG00000244575 | IGKV1‐27 | IG_V_gene | 2.01 | 9.16E‐05 | 6.04E‐03 |
| ENSG00000167034 | NKX3.1 | protein_coding | −2.04 | 0.00204 | 3.25E‐02 |
P adj ≤0.05 and fold change ≥±1.5 were considered significant, and the list with fold change ≥±2 is shown. A positive fold change means that the affected gene is overexpressed in CASES. A negative fold change means that the affected gene is overexpressed in CONTROLS. P adj indicates adjusted P value corrected for multiple testing using the Benjamini and Hochberg method in DESeq2.