Table 1.
Study Population Demographics With Characteristics: BP‐Guideline Nonadherent vs BP‐Guideline Adherent Cohorts
| Variables | Overall n=265 409 | BP‐guideline nonadherent n=106 899 | BP‐guideline adherent n=158 510 | P values |
|---|---|---|---|---|
| Age, mean (SD), y | 70.6 (14.7) | 70.7 (15.3) | 70.6 (14.3) | 0.237 |
| Sex, female, % | 50.3 | 50.0 | 50.5 | 0.030 |
| Race or ethnicity, % | ||||
| White | 68.6 | 66.3 | 70.1 | <0.001 |
| Black | 17.6 | 20.7 | 15.5 | |
| Hispanic | 13.8 | 13.0 | 14.36 | |
| Index event type,* % | ||||
| Transient ischemic attack | 10.9 | 10.8 | 11 | 0.022 |
| Acute ischemic stroke | 73.7 | 73.6 | 73.8 | |
| Subarachnoid hemorrhage | 3.9 | 3.9 | 3.9 | |
| Intracerebral hemorrhage | 11.3 | 11.6 | 11.1 | |
| Acute ischemic stroke pathogenesis (TOAST criteria), % | ||||
| Cardioembolism | 7.5 | 8.2 | 7.0 | <0.001 |
| Cryptogenic | 8.8 | 8.8 | 8.8 | |
| Large‐vessel atherosclerosis | 5.7 | 5.9 | 6.9 | |
| Small‐vessel occlusion | 6.4 | 5.6 | 6.9 | |
| Stroke of other determined | 1.0 | 1.1 | 1 | |
| Unknown stroke pathogenesis subtype | 70.5 | 70.4 | 70.6 | |
| Insurance, % | ||||
| Private | 38.2 | 37.5 | 38.6 | <0.001 |
| Medicare | 44.2 | 45 | 43.5 | |
| Medicaid | 5.0 | 5.1 | 5.0 | |
| Self‐pay | 10.4 | 10.0 | 10.9 | |
| Diabetes, % | 31.8 | 37.6 | 27.8 | <0.001 |
| Atrial fibrillation/flutter, % | 18.3 | 23.5 | 14.9 | <0.001 |
| Stroke or TIA before index event, % | 29.4 | 30.1 | 28.9 | <0.001 |
| Discharged home | 48.4 | 44.2 | 51.3 | <0.001 |
| mRS score at discharge | ||||
| mRS 0–2 | 43.4 | 39.7 | 45.8 | <0.001 |
| mRS 3–5 | 51.3 | 50.9 | 51.5 | |
| mRS 6 | 5.4 | 9.3 | 2.7 |
Diagnosis of diabetes and atrial fibrillation based on discharge ICD diagnostic codes.
BP‐guideline adherent: percentage of patients who were prescribed guideline‐based therapy as determined by 5 simple guideline‐derived rules.
Acute ischemic stroke subtypes are based on the included discharge diagnosis codes. The stroke pathogenesis for acute ischemic stroke based on TOAST is a prespecified field in the data. The Unknown stroke pathogenesis subtype was specifically selected for the data set and does not represent missing data. BP indicates blood pressure; ICD, International Classification of Diseases; mRS, modified Rankin scale; TIA, transient ischemic attack; and TOAST, Trial of ORG 10172 in Acute Stroke Treatment.
Index event type refers to the hospitalization event that resulted in the case inclusion in the Florida Stroke Registry, which is based on the discharge ICD diagnosis codes.