Table 1.
Patient Characteristics of Donors of LA and RA Samples
| LA (n=75) | RA (n=56) | LA+RA (n=20) | P value | |
|---|---|---|---|---|
| Sex, female | 25 (33.3) | 12 (24.4) | 3 (15.0) | 0.373 |
| Age, y | 63.6±10.4 | 65.8±10.2 | 61.5±13.0 | 0.261 |
| Weight, kg | 76.8±14.9 | 80.1±16.2 | 79.9±16.8 | 0.470 |
| Height, cm | 173.4±9.6 | 174.2±10.1 | 174.8±10.6 | 0.421 |
| Body mass index | 26.0±3.9 | 26.5±4.2 | 26.2±3.8 | 0.524 |
| Rhythm | 0.398 | |||
| NoAF | 31 (41.3) | 36 (64.3) | 9 (45.0) | |
| pAF | 24 (32.0) | 13 (23.2) | 5 (25.0) | |
| persAF | 20 (26.7) | 9 (16.0) | 6 (30.0) | |
| PVI | 18 (24.0) | 4 (7.1) | 2 (10) | 0.042 |
| Heart failure | 27 (36.0) | 14 (25.0) | 12 (60.0) | 0.045 |
| NYHA class | 2.3±1.1 | 2.4±1.1 | 2.8±1.1 | 0.102 |
| HTX | 22 (29.3) | 7 (12.5) | 10 (50.0) | 0.007 |
| CHA2DS2‐VASc | 2.9±1.4 | 2.9±1.5 | 2.4±1.5 | 0.227 |
| CAD | 32 (42.7) | 37 (66.1) | 8 (40.0) | 0.020 |
| CABG | 16 (21.3) | 27 (48.2) | 4 (20.0) | 0.003 |
| Prior MI | 18 (24.0) | 10 (17.9) | 4 (20.0) | 0.555 |
| Diabetes | 17 (22.7) | 10 (17.9) | 1 (5.0) | 0.349 |
| Chronic kidney failure | 8 (10.7) | 5 (8.9) | 0 (0.0) | 0.353 |
| Hypertension | 56 (74.6) | 48 (85.7) | 8 (40.0) | 0.001 |
| Prior stroke | 10 (13.3) | 4 (7.1) | 0 (0.0) | 0.136 |
| Prior TIA | 2 (2.7) | 7 (12.5) | 1 (5.0) | 0.086 |
| Thyroid disease | 11 (14.7) | 2 (3.6) | 4 (20.0) | 0.445 |
| MV stenosis | 3 (4.0) | 3 (5.4) | 0 (0.0) | 0.013 |
| MV regurgitation | 0.065 | |||
| Grade 1 | 13 (17.3) | 11 (19.6) | 5 (25.0) | |
| Grade 2 | 12 (16.0) | 8 (14.3) | 2 (10.0) | |
| Grade 3 | 9 (12.0) | 7 (12.5) | 2 (10.0) | |
| Grade 4 | 8 (10.7) | 1 (1.8) | 5 (25.0) | |
| MV surgery | 19 (25.3) | 7 (12.5) | 7 (35.0) | 0.114 |
| AV stenosis | 15 (20.0) | 19 (33.9) | 1 (5.0) | 0.001 |
| AV regurgitation | 18 (24.0) | 17 (30.3) | 4 (20.0) | 0.092 |
| AV surgery | 18 (24.0) | 20 (35.8) | 1 (5.00) | 0.014 |
| TV regurgitation | 23 (30.7) | 11 (19.6) | 7 (35.0) | 0.427 |
Values are presented as mean±SD for continuous traits or in absolute number (percentage) for dichotomous traits. P values were calculated applying 1‐way ANOVA or chi‐square testing. AV indicates aortic valve; CABG, coronary artery bypass graft; CAD, coronary artery disease; HTX, heart transplant xenograft; LA, left atrial; MI, myocardial infarction; MV, mitral valve; NoAF, no history of AF; NYHA, New York Heart Association; pAF, paroxysmal AF; persAF, persistent/permanent AF; PVI, concomitant pulmonary vein isolation; RA, right atrial; TIA, transient ischemic attack; and TV, tricuspid valve.