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. 2023 Nov 20;12(22):e032689. doi: 10.1161/JAHA.123.032689

Figure 1. The frequency of cognitive impairment among patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), stratified by age.

Figure 1

A, Patients were stratified according to their APOE genotype and age group. B, Patients were stratified according to their pathogenic NOTCH3 variant and age group. The 95% CI for the proportion of cognitive impairment in each subgroup was calculated using the binomial distribution method. Cognitive impairment was defined as a Mini‐Mental State Examination score <24 for patients with CADASIL.