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. 2023 Oct 18;12(21):e029799. doi: 10.1161/JAHA.123.029799

Table 1.

Demographics, Comorbidities, and Stroke Causes and Localization

Women (n=160) Men (n=140) P value
Demographic
Mean age, y 78±12 71±14 <0.01
Race
Asian 1 (0.6%) 1 (0.7%)
Black 69 (43%) 67 (48%)
White 84 (53%) 70 (50%)
Other 6 (4%) 2 (1%) 0.58
BMI 27.8±8.3 28±6.2 0.75
Hand dominance (R) 98/103 (95%) 82/96 (82%) 0.02
Comorbidities
Hypertension 140 (88%) 126 (90%) 0.50
Diabetes 59 (37%) 67 (48%) 0.06
Dyslipidemia 89 (56%) 94 (67%) 0.04
Smoking (prior and current) 59 (37%) 77 (55%) <0.01
Chronic kidney disease 54 (34%) 53 (38%) 0.46
Coronary artery disease 40 (25%) 49 (35%) 0.06
Chronic heart failure 35 (22%) 40 (29%) 0.18
Atrial fibrillation/flutter 45 (28%) 36 (26%) 0.64
Stroke/TIA 47 (20%) 44 (31%) 0.70
NIHSS at admission 6 (2–14) 5 (3–11) 0.21
Stroke causes
LAA 17 (11%) 11 (8%)
Cardioembolic 65 (41%) 44 (32%)
SVO 18 (11%) 22 (16%)
Cryptogenic
Multiple causes 25 (15%) 12 (8%)
ESUS 22 (14%) 46 (33%)
Incomplete work‐up 10 (6%) 2 (1%)
Others (hypercoagulability) 3 (2%) 3 (2%) <0.01
Insula involvement 51/159 (32%) 37/140 (26%) 0.28
R Insula involvement 32/159 (20%) 15/140 (11%) 0.02
Side of stroke
Left 58 (36%) 66 (47%)
Right 82 (51%) 49 (35%)
Bilateral 20 (12.5%) 25 (18%) 0.02

Categorical variables are presented as frequency (column percent), continuous variables are presented as mean±SD, or median and interquartile range when nonnormally distributed. BMI indicates body mass index; ESUS, embolic stroke of undetermined source; LAA, large artery atherosclerosis; NIHSS, National Institutes of Health Stroke Scale; R, right; SVO, small vessel occlusion; and TIA, transient ischemic attack.