Table 1.
Demographic and Clinical Characteristics of Patients With COVID‐19, Overall and by COVID‐19 Outcomes, PCORnet, March 2020 to February 2022
| Characteristic | All COVID‐19 | Hospitalization | Critical care | Mechanical ventilation | 60‐day mortality* | |
|---|---|---|---|---|---|---|
| Number of unique patients | 1 494 837 | 100% | 188 188 (12.6%) | 43 357 (2.9%) | 22 346 (1.5%) | 31 094 (2.1%) |
| Age group | ||||||
| 20–39 y | 607 239 | 41% | 18% | 12% | 10% | 3% |
| 40–54 y | 388 201 | 26% | 19% | 19% | 19% | 10% |
| 55–64 y | 230 500 | 15% | 20% | 22% | 24% | 17% |
| 65–74 y | 153 868 | 10% | 20% | 24% | 27% | 26% |
| 75–84 y | 81 232 | 5% | 15% | 16% | 16% | 26% |
| 85+ y | 33 797 | 2% | 8% | 7% | 5% | 19% |
| Sex† | ||||||
| Female | 835 254 | 56% | 50% | 42% | 39% | 42% |
| Male | 659 026 | 44% | 50% | 58% | 61% | 58% |
| Hispanic ethnicity† | ||||||
| Yes | 249 445 | 17% | 19% | 16% | 20% | 16% |
| No | 1 106 884 | 74% | 76% | 79% | 73% | 77% |
| Race† | ||||||
| Asian | 42 665 | 3% | 3% | 3% | 3% | 3% |
| Black | 245 015 | 16% | 23% | 23% | 23% | 21% |
| White | 942 985 | 63% | 53% | 57% | 51% | 56% |
| Pandemic phase | ||||||
| March 1, 2020–April 30, 2020 | 59 836 | 4% | 11% | 12% | 20% | 19% |
| May 1, 2020–February 28, 2021 | 660 518 | 44% | 41% | 40% | 39% | 39% |
| March 1, 2021–Jun 30, 2021 | 89 500 | 6% | 10% | 9% | 8% | 7% |
| July 1, 2021–December 19, 2021 | 270 093 | 18% | 20% | 23% | 21% | 20% |
| December 20, 2021–February 28, 2022 | 414 890 | 28% | 18% | 17% | 12% | 15% |
| Hypertension | ||||||
| No hypertension | 857 014 | 57% | 40% | 35% | 42% | 32% |
| All hypertension‡ | 637 823 | 43% | 61% | 65% | 58% | 69% |
| Diabetes | ||||||
| No diabetes | 1 311 676 | 88% | 69% | 58% | 57% | 59% |
| All diabetes‡ | 183 161 | 12% | 32% | 41% | 43% | 42% |
| Other comorbidities§ | ||||||
| Combined Comorbidity Index score (mean) | 1 494 837 | 1.1 | 3.4 | 4.7 | 4.8 | 5.2 |
| Chronic pulmonary disorders | 197 721 | 13% | 25% | 29% | 28% | 29% |
| Mental health disorders | 187 948 | 13% | 20% | 21% | 19% | 20% |
| Anemia | 141 639 | 9% | 26% | 33% | 35% | 34% |
| Arrythmia | 136 473 | 9% | 29% | 43% | 45% | 47% |
| Asthma | 119 764 | 8% | 12% | 11% | 11% | 9% |
| Severe obesity (BMI ≥40 kg/m2) | 117 400 | 8% | 16% | 20% | 21% | 15% |
| Coronary artery disease | 100 203 | 7% | 22% | 28% | 26% | 33% |
| Chronic kidney disease | 91 538 | 6% | 23% | 29% | 29% | 35% |
| Cancer | 69 582 | 5% | 11% | 12% | 10% | 17% |
| Congestive heart failure | 73 737 | 5% | 19% | 27% | 27% | 31% |
| Pregnancy | 70 442 | 5% | 6% | 1% | 1% | 0% |
| Smoking status | ||||||
| Current smoker | 72 359 | 5% | 5% | 5% | 4% | 3% |
| Former smoker | 146 896 | 10% | 13% | 16% | 13% | 16% |
| Never smoker | 506 885 | 34% | 24% | 29% | 21% | 21% |
| Unknown or missing | 768 697 | 51% | 58% | 51% | 62% | 60% |
| COVID‐19 treatments | ||||||
| Dexamethasone | 107 777 | 7% | 40% | 54% | 52% | 44% |
| Monoclonal antibodies | 34 682 | 2% | 2% | 2% | 1% | 1% |
| Remdesivir | 66 210 | 4% | 29% | 39% | 38% | 30% |
| BMI | ||||||
| <30 kg/m2 | 426 797 | 29% | 37% | 41% | 34% | 42% |
| ≥30 kg/m2 | 363 352 | 24% | 34% | 39% | 38% | 30% |
| BMI missingǁ | 704 688 | 47% | 28% | 20% | 28% | 29% |
60‐day mortality refers to in‐hospital mortality.
Missing and “Other” not shown.
All hypertension and diabetes included patients who did not have a documented blood pressure measurement or glycated hemoglobin, respectively, within 18 months before COVID‐19, so control status could not be categorized.
Comorbidities with prevalence ≥5% are displayed; other comorbidities with prevalence <5% included rheumatoid arthritis, systemic lupus erythematosus, seizures or epilepsy, alcohol use disorder, chronic obstructive pulmonary disease, cirrhosis, dementia, Down syndrome, end‐stage renal disease, HIV, hemiplegia, inflammatory bowel disorder, multiple sclerosis, peripheral vascular disorders, Parkinson disease, pulmonary circulation disorders, chronic pulmonary disorders, sickle cell disease, or weight loss.
BMI was missing if patients did not have a recorded height and weight within 18 months of the index positive test.
BMI indicates body mass index; and PCORnet, National Patient‐Centered Clinical Research Network.