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. 2023 Dec 15;102(50):e36647. doi: 10.1097/MD.0000000000036647

Table 1.

Characteristics of the included studies.

Authors/yr of publication Country Female (%) Age, yr (mean ± SD or range) Study design Number of patients Mean follow-up time (yr) Mean tumor diameter (cm)
TT LT TT LT TT LT TT LT
Hay/2008 USA 627 (69.7) 46 Cohort 765 125 17.2 0.7
Lee/2013 Korea 908 (89.7) 45.3 Cohort 506 506 11.8 0.61 0.59
Donatini/2016 France 717 (81.4) 48.5 (19–90) 44.2 (11–80) Cohort 251 69 10.8 11.2 0.78 0.71
Dobrinja/2017 Italy 80 (76.2) 54 (12–77) 56 (30–79) Cohort 86 19 4.8 5.3 0.53 0.6
Kim/2017 Korea 7057 (81.3) 48.3 ± 10.4 45.5 ± 10.5 Cohort 5387 3289 5.4 0.6 ± 0.2 0.5 ± 0.2
Kwon/2017 Korea 1256 (91.3) 47 (41–54) Cohort 688 688 8.5 0.6 0.6
Xu/2018 China 2739 (75.9) 47.5 ± 12.0 Cohort 1868 1706 5.7 0.6 ± 0.3
Jeon/2019 Korea 226 (88.6) 47.65 ± 10.39 47.65 ± 10.39 Cohort 128 127 8 7.9 0.67 ± 0.2 0.63 ± 0.2

LT = lobectomy, TT = total thyroidectomy.