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. Author manuscript; available in PMC: 2024 May 10.
Published in final edited form as: ACS Appl Mater Interfaces. 2023 Apr 28;15(18):21877–21892. doi: 10.1021/acsami.3c01501

Figure 6.

Figure 6.

LNP B6 enables potent intracellular delivery of K27-D30—and other DARPins—to multiple cancer cell lines in vitro. (A) Intracellular delivery—%GFP+ cells (left axis) and mean fluorescence intensity (right axis, normalized to untreated cells)—of K27-D30 to multiple cancer cell lines in vitro. Delivery efficiency of B6 is dependent on cell line. (B) Intracellular delivery of multiple DARPin cargos to HCT116 cells in vitro. Delivery efficiency of B6 is dependent on macromolecular cargo. n ≧ 4.