Fig. 1.

Illustration of in vitro co-culture experimental setup with human adenocarcinoma cells (Caco-2 cells) in the apical chamber and peripheral blood mononuclear cells (PBMCs) isolated from human blood in the basolateral chamber. The inflammatory response was stimulated with the addition of lipopolysaccharide (LPS) in the basolateral chamber and the fermentation supernatants of Tritordeum breads BYB and SDB), represented here as test substrates, were incubated on the apical side containing Caco-2 monolayer.