Table 1.
Patient characteristics.
| Arm A (N = 41) | Arm B (N = 18) | Total (N = 59) | |
|---|---|---|---|
| Age, years | |||
| Median | 58.5 | 60.2 | 59.5 |
| Range | 44–74 | 46–76 | 44–76 |
| Sex, n (%) | |||
| Male | 32 (78%) | 15 (83%) | 47 (80%) |
| Female | 9 (22%) | 3 (17%) | 12 (20%) |
| ECOG status, n (%) | |||
| Unknown | 1 (2%) | 0 | 1 (2%) |
| 0 | 27 (66%) | 13 (75%) | 40 (68%) |
| 1 | 13 (32%) | 5 (25%) | 18 (31%) |
| Smoker, n (%) | |||
| Current | 24 (59%) | 7 (39%) | 31 (53%) |
| Former | 12 (29%) | 8 (44%) | 20 (34%) |
| Never | 5 (12%) | 3 (17%) | 8 (14%) |
| Alcohol consumption, n (%) | |||
| Current | 22 (54%) | 10 (56%) | 32 (54%) |
| Former | 13 (32%) | 4 (22%) | 17 (29%) |
| Never | 6 (15%) | 4 (22%) | 10 (17%) |
| Primary tumor site, n (%) | |||
| Oral cavity | 26 (63%) | 12 (67%) | 38 (64%) |
| Larynx | 0 | 1 (6%) | 1 (2%) |
| Oropharynx | 11 (27%) | 3 (17%) | 14 (24%) |
| Hypopharynx | 4 (10%) | 2 (11%) | 6 (10%) |
| Histologic grade, n (%) | |||
| Unknown | 1 (2%) | 0 | 1 (2%) |
| Well differentiated | 21 (51%) | 11 (61%) | 32 (54%) |
| Moderately differentiated | 12 (29%) | 5 (28%) | 17 (29%) |
| Poorly differentiated | 7 (17%) | 2 (11%) | 9 (15%) |
| HPV status, n (%) | |||
| Unknown | 6 (15%) | 0 | 6 (10%) |
| HPV negative | 30 (73%) | 16 (89%) | 46 (78%) |
| HPV positive | 5 (12%) | 2 (11%) | 7 (12%) |
| Pretreatment T-stagea, n (%) | |||
| T1 | 1 (2%) | 0 | 1 (2%) |
| T2 | 15 (37%) | 4 (22%) | 19 (32%) |
| T3 | 5 (12%) | 4 (22%) | 9 (15%) |
| T4 | 20 (49%) | 10 (56%) | 30 (51%) |
| Pretreatment N-stagea, n (%) | |||
| N0 | 17 (41%) | 12 (67%) | 29 (49%) |
| N1 | 5 (12%) | 2 (11%) | 7 (12%) |
| N2 | 19 (46%) | 4 (22%) | 23 (39%) |
aAmerican Joint Committee on Cancer, 7th edition staging.