Fig. 4. Dysregulation of adulthood repetitive behavior specifically in male mice treated with B. fragilis.

Behavioral analysis of eight-week-old B. fragilis-treated mice. a Total number of marbles buried by male mice in a 30 min period b Time spent grooming in an open field arena by male mice in a ten minute period in open field arena. c Time spent in the middle of an open field arena by male mice in a 10 min period. d Total Distance Traveled by male mice in an open field arena in a 10 min period. e Total number of marbles buried by female mice in a 30 min period. f Time spent grooming in an open field arena by female mice in a ten minute period in open field arena. g Time spent in the middle of an open field arena by female mice in a 10 min period. h Total Distance Traveled by female mice in an open field arena in a 10 min period. Two tailed student’s t-test **=p < 0.01 ***=p < 0.001 n = 11 per group. Error bars represent standard error of the mean.