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. 2023 Dec 19;14:8423. doi: 10.1038/s41467-023-44152-8

Fig. 4. Nur77-GFPHI and Nur77-GFPLO CD4 T cells differ in expression of TCR clonotypes.

Fig. 4

a Relative abundance of top 10 clonotypes from single-cell TCR-Sequencing of Nur77-GFPLO and Nur77-GFPHI CD4 T cells sorted from the lungs of one Nur77-GFP mouse at four weeks post-infection. Samples sorted on live CD3+CD4+CD44+ Nur77-GFPLO or Nur77-GFPHI cells. Amino acid sequences represent TCR CDR3 regions expressed as “TCRα_TCRβ“. b Feature plots show the localization of three expanded TCR clonotypes on gene expression UMAPs from Nur77-GFPLO and Nur77-GFPHI CD4 T cells. c Scatter plot shows the prevalence of TCR clonotypes among Nur77-GFPLO vs. Nur77-GFPHI cells. Blue dots indicate expanded clonotypes. Circle size indicates total abundance of each expanded clonotype.