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. 2023 Dec 18;6:1280. doi: 10.1038/s42003-023-05679-0

Table 2.

Thermodynamic parameters of XcAP-1, −2, and −3 binding to biogenic amines in the presence or absence of saturating concentrations of LTC4.

Protein Ligand K (M−1) ΔH (cal/mol) ΔS (cal/mol/deg)
XcAP-1 Serotonin 1.69  ×  108 ± 8.97 × 107 −1.573 × 104 ± 536.1 − 14.2
LTC4/Serotonin 5.48 × 108 ± 3.01 × 107 −1.598 × 104 ± 390.6 − 12.7
XcAP-2 Histamine 2.28 × 107 ± 6.08 × 106 −2.112 × 104 ± 718.5 −36.0
LTC4/Histamine 4.07 × 107 ± 7.83 × 106 −2.057 × 104 ± 397.2 −33.0
XcAP-3 Histamine 3.43 × 107 ± 9.18 × 106 −1.509 × 104 ± 402.3 −15.3
LTC4/Histamine 7.35 × 107 ± 2.86 × 107 −1.436 × 104 ± 434.2 −11.4