Skip to main content
. 2023 Dec 18;14(12):839. doi: 10.1038/s41419-023-06300-2

Fig. 8. Mechanism diagram of imatinib (IM) inducing ferroptosis. IM upregulates STUB1 expression.

Fig. 8

STUB1 overexpression promotes the ubiquitination of GPX4, thereby inducing ferroptosis in gastrointestinal stromal tumors (GIST).