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. 2023 Dec 5;14:1272471. doi: 10.3389/fimmu.2023.1272471

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Copyright © 2023 Pitta, Angst, Pinheiro, Vieira, Spitz, Andrade, Carvalho, Hacker, Sarno and Jardim

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased levels of IL-1β and IL-17 are associated with Pain in patients with neural pure form of the disease. Samples from neural pure patients were according the presence or not of pain. Serum levels of IL-10, IL-1β, IL-6, TNF, IL-17, MCP-1, IFN-ϒ, IP-10 and, TGF-β were evaluated by ELISA. The results were showed in a Scatter plot with the median of each group. Significance of the difference between the two groups evaluated were considered when p < 0.05.