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Illustrative adiposopathic factors that may contribute to hypertension. Beyond the adverse biomechanical effects of fat mass alone shown in Fig. 2, positive caloric balance may lead to adipocyte hypertrophy and adipose tissue accumulation with pathogenic adipose tissue (including perivascular adipose tissue) [23] endocrine and immune factors that may contribute to hypertension. 11β-HSD1: beta-hydroxysteroid dehydrogenase type 1.
