Figure 2.

Cross-lagged autoregressive path models examining the directionality of association between relapse and stressful life events

Stressful life event status and number of relapse events in the saturated (A) and reduced (B) models, and number of stressful life events and number of relapse events in the saturated (C) and reduced (D) models. Models controlled for medication adherence, cannabis use, other drug use, and pre-onset stressful life events. The saturated path model included all paths to endogenous variables and the reduced model included only statistically significant (p≤0·05) paths. The numbers on the arrows represent regression coefficient estimates (β). *p≤0·05. †p≤0·01.