Table 3.

Meta-regression of participant characteristics

Variable	Meta-regression ΔPWV (uncontrolled)			Meta-regression controlled for age, sex at birth, baseline PWV and presence of long-term conditions
	N=	Estimate (95% CI)	P value	N=	Estimate (95% CI)	P value
Age	100	0.01 (−0.02 to −0.005)	0.0005*	98	0.01 (−0.02 to −0.003)	0.008*
Sex at birth	99	0.001 (−0.004 to 0.002)	0.46	98	0.003 (−0.006 to 0.0004)	0.10
BMI	89	0.0003 (−0.03 to 0.03)	0.99	84	0.02 (−0.01 to 0.06)	0.22
Systolic blood pressure	97	0.01 (−0.02 to −0.0009)	0.03*	91	0.004 (−0.01 to 0.02)	0.59
Cholesterol	51	0.02 (−0.10 to 0.15)	0.74	46	0.03 (−0.18 to 0.12)	0.73
HbA1c	21	0.01 (−0.03 to 0.008)	0.26	18	0.007 (−0.25 to 0.26)	0.96
VO2 max	65	0.01 (−0.006 to 0.03)	0.23	61	0.004 (−0.03 to 0.02)	0.78

*p≤0.05.

BMI, body mass index; HbA1C, Glycosylated Haemoglobin; PWV, pulse wave velocity; VO2 max, maximum rate of oxygen consumption.