Table 2.
Multivariate mixed regression models for HbA1c
| Variable | Total sample (n=156) |
HbA1c<7.5% (n=68) |
HbA1c≥7.5% (n=88) |
|||
| B (95%CI) | P value | B (95% CI) | P value | B (95% CI) | P value | |
| Time | ||||||
| M3 (ref: M0) | 0.03 (−0.18 to 0.24) | 0.765 | 0.03 (−0.09 to 0.16) | 0.611 | −0.46 (−0.69 to −0.23) | <0.001 |
| M6 (ref: M0) | 0.1 (−0.11 to 0.32) | 0.344 | 0.10 (−0.03 to 0.23) | 0.115 | −0.49 (−0.73 to −0.25) | <0.001 |
| M12 (ref: M0) | 0.32 (0.10 to 0.55) | 0.005 | 0.32 (0.18 to 0.47) | <0.001 | −0.43 (−0.68 to −0.19) | 0.001 |
| Duration of T1DM | 0.05 (0.007 to 0.09) | 0.020 | −0.005 (−0.04 to 0.03) | 0.762 | 0.09 (0.02 to 0.15) | 0.011 |
| Presence of comorbidities | −0.10 (−0.39 to 0.18) | 0.477 | 0.09 (−0.13 to 0.30) | 0.439 | −0.22 (−0.70 to 0.26) |
0.372 |
| Age group: ≥12 years (ref: <12 years) | 0.17 (−0.12 to 0.47) | 0.253 | 0.09 (−0.15 to 0.32) | 0.473 | 0.26 (−0.21 to 0.73) | 0.274 |
| Baseline HbA1c group: ≥7.5% (ref: HbA1c<7.5%) | 1.81 (1.50 to 2.13) | <0.001 | ||||
| Time×baseline HbA1c Group (ref: M0 and HbA1c<7.5%) | ||||||
| M3 and HbA1c≥7.5% | −0.49 (−0.78 to −0.21) | <0.001 | ||||
| M6 and HbA1c≥7.5% | −0.59 (−0.88 to −0.29) | <0.001 | ||||
| M12 and HbA1c≥7.5% | −0.76 (−1.05 to −0.46) | <0.001 | ||||
| Intercept | 6.75 (6.41 to 7.09) | <0.001 | 6.73 (6.50 to 6.96) | <0.001 | 8.53 (8.12 to 8.94) | <0.001 |
HbA1c, glycated haemoglobin; M, month; T1DM, type 1 diabetes mellitus.