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. 2023 Nov 28;20(1):7. doi: 10.3892/mco.2023.2705

Figure 1.

Figure 1

Pharmacological mechanism of lenalidomide. *Co-stimulation of CD4+ and CD8+ T cells. MM, multiple myeloma; VEGF, vascular endothelial growth factor; IL, interleukin; NKT, natural killer cells and T lymphocytes; C/EBP-β CCAAT/, enhancer binding protein-β; NF-κB, nuclear factor-κB; BMSC, bone marrow stromal cell; PBMC, human peripheral blood mononuclear cell; TNF-α, tumor necrosis factor-Α; PD-1 programmed death-1; PD-L1, programmed death ligand-1.