Fig. 5.

WJ-MSCs attenuate ConA-induced autoimmune hepatitis by regulating T and inflammation. A–D The quantification of T lymphocyte subsets (CD4⁺T, CD8⁺T, CD4/CD8 and Treg) in peripheral blood from mice were detected by flow cytometry. n = 5 in each group. E Quantification of CD4 or CD8-positive cells from liver in four group mice, wild-type, PBS-, WJ-MSCs11- and WJ-MSCs45- treatment after ConA injection. n = 6 in each group. Scale bar: 20 μm. F, G Transcriptome analysis of IL-1β, TNF, IFNAR1 and Foxp3 from liver in four group mice, wild-type, PBS, WJ-MSCs11 and WJ-MSCs45 treatment after ConA injection. n = 3 in each group. t tests were performed. Statistical significance is indicated by ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001