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. 2023 Dec 18;21:504. doi: 10.1186/s12916-023-03227-5

Fig. 2.

Fig. 2

Mendelian randomization estimates for the association of genetically proxied SLC13A5 inhibition with kidney traits. Mendelian randomization estimates are scaled per 1-standard deviation (SD) increase in plasma citrate through genetically proxied SLC13A5 inhibition. The units for the BUN, creatinine-eGFR, cystatin C-eGFR and uACR are SD change in log transformed levels. The units for CKD and microalbuminuria are log odds ratio. Raw p values are presented. BUN: blood urea nitrogen, chronic kidney disease; eGFR: estimated glomerular filtration rate, urine albumin-creatinine ratio