Table 3.
Univariable logistic regression analysis of general characteristics for ICU and hospital mortality
| ICU mortality | Hospital mortality | ||||
|---|---|---|---|---|---|
| Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | ||
| CPB time (ref, non CPB (CPB = 0)) | |||||
| Short CPB time | 4.19 (1.15–15.28) | 0.030 | 1.64 (0.79–3.44) | 0.188 | |
| Long CPB time | 8.67 (2.47–30.41) | 0.001 | 2.70 (1.30–5.62) | 0.008 | |
| Male (ref, female) | 0.53 (0.25–1.16) | 0.111 | 0.70 (0.39–1.27) | 0.245 | |
| Age category (ref, ≤ 45 years) | |||||
| 45 to 70 years | 0.64 (0.28–1.44) | 0.280 | 0.71 (0.34–1.47) | 0.356 | |
| ≥ 70 years | 0.33 (0.10–1.06) | 0.062 | 0.75 (0.31–1.83) | 0.524 | |
| BMI category (ref, Normal (18.4 to 23.9)) | |||||
| Underweight (≤ 18.4) | 2.00 (0.53–7.54) | 0.306 | 2.05 (0.57–7.41) | 0.271 | |
| Overweight (23.9–27.9) | 1.10 (0.51–2.35) | 0.825 | 0.60 (0.32–1.13) | 0.115 | |
| Obesity (≥ 27.9) | 0.32 (0.32–2.37) | 0.792 | 0.46 (0.20–1.03) | 0.060 | |
| Comorbidity | |||||
| Smoking | 0.91 (0.46–1.81) | 0.790 | 1.13 (0.64–1.99) | 0.671 | |
| Hypertension | 1.44 (0.73–2.44) | 0.291 | 1.02 (0.59–1.77) | 0.949 | |
| Diabetes | 0.96 (0.42–2.19) | 0.927 | 0.84 (0.43–1.66) | 0.621 | |
| Cerebrovascular disease | 0.62 (0.20–1.90) | 0.405 | 0.95 (0.42–2.15) | 0.896 | |
| Chronic lung disease | 2.24 (0.71–7.05) | 0.169 | 1.04 (0.35–3.12) | 0.940 | |
| Coronary heart disease | 1.10 (0.56–2.15) | 0.791 | 1.05 (0.60–1.82) | 0.878 | |
| Valve disease | 1.90 (0.41–2.89) | 0.862 | 1.13 (0.50–2.54) | 0.775 | |
| Preoperative LVEF (ref, LVEF ≥ 50%) | 2.05 (0.77–5.45) | 0.148 | 1.60 (0.65–3.95) | 0.308 | |
| NYHA | 1.49 (0.76–2.94) | 0.247 | 2.46 (1.38–4.39) | 0.002 | |
| Preoperative drug therapy | |||||
| ACEI | 0.75 (0.35–1.60) | 0.460 | 1.00 (0.55–1.83) | 0.995 | |
| β-blocker | 0.97 (0.50–1.89) | 0.930 | 0.76 (0.44–1.32) | 0.325 | |
| CCB | 1.41 (0.70–2.83) | 0.341 | 1.02 (0.56–1.84) | 0.956 | |
| Aspirin | 0.99 (0.35–2.83) | 0.988 | 1.20 (0.51–2.82) | 0.679 | |
| Statins | 0.39 (0.17–0.90) | 0.027 | 0.67 (0.37–1.21) | 0.180 | |
| Operation type (ref, CABG) | |||||
| Valve replacement | 1.96 (0.79–4.84) | 0.145 | 2.04 (1.00-4.16) | 0.049 | |
| Ascending aorta replacement | 1.71 (0.70–4.21) | 0.240 | 1.05 (0.52–2.14) | 0.885 | |
| Other | 2.57 (0.56–11.82) | 0.225 | 2.80 (0.71–10.97) | 0.141 | |
| Operation time | 1.17 (1.05–1.32) | 0.007 | 1.08 (0.98–1.20) | 0.139 | |
| Aortic clamping time | 1.00 (0.99–1.01) | 0.117 | 1.00 (0.99-1.00) | 0.238 | |
| Blood loss (ref, 800 ml) | 1.21 (0.62–2.35) | 0.581 | 1.08 (0.98–1.20) | 0.139 | |
| RBC infusion (U) | 1.01 (0.98–1.04) | 0.419 | 1.10 (0.64–1.91) | 0.725 | |
Short CPB time = 0 < CPB < 173 min, long CPB time = CPB 173 ≥ minutes