Table 5.
Multivariable Cox regression analysis for ICU and hospital mortality grouped by CPB category
| Variable | Crude | Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|---|---|
| HR (95%CIs) | P value | HR (95%CIs) | P value | HR (95%CIs) | P value | |||
| ICU mortality | ||||||||
| Non-CPB | 1 (ref) | 1 (ref) | 1 (ref) | |||||
| Short CPB time | 3.74 (1.08–12.91) | 0.037 | 3.38 (0.96–11.91) | 0.058 | 15.12 (3.07–74.48) | 0.001 | ||
| Long CPB time | 7.17 (2.17–23.69) | 0.001 | 6.49 (1.91–20.09) | 0.003 | 35.29 (6.66-181.71) | < 0.001 | ||
| Hospital mortality | ||||||||
| Non-CPB | 1 (ref) | 1 (ref) | 1 (ref) | |||||
| Short CPB time | 1.48 (0.81–2.71) | 0.203 | 1.27 (0.68–2.38) | 0.449 | 3.21 (1.11–9.32) | 0.032 | ||
| Long CPB time | 2.23 (1.25–3.98) | 0.006 | 2.14 (1.17–3.92) | 0.014 | 6.51 (1.97–21.47) | 0.002 | ||
Short CPB time = 0 < CPB < 173 min, long CPB time = CPB 173 ≥ minutes
Model1: The results were adjusted by age, gender, BMI;
Model2: The results were adjusted by age, gender, BMI, smoking, hypertension, diabetes, cerebrovascular disease, chronic lung disease, coronary heart disease, valve disease, ACEI, β_blocker, CCB, aspirin, statins, preoperative LVEF, NYHA, operation type, aortic clamping time, operation time, blood loss, transfusion of RBCModel1: The results were adjusted by age, gender, BMI;