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Comparison of pharmacokinetics of brexanolone and zuranolone.
| Brexanolone IP | Zuranolone IP | Zuranolone PO | |
|---|---|---|---|
| Dose | 90 μg/kg/h in 60 h | 10 mg/kg | 10 mg/kg |
| C max 1 | 89.7 ng/mL | 3,197 ng/mL | 1,335 ng/mL |
| t max 2 | 47.8 h | 30 min | 30 min |
BIBLIOGRAPHY \l 1045 1Maximum plasma concentration; 2Time to achieve maximum plasma concentration.
