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. 2023 Dec 7;5(6):fcad344. doi: 10.1093/braincomms/fcad344

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© The Author(s) 2023. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of differentially expressed genes. (A) Number of genes upregulated [right; log₂FC ≥ 1; false-discovery rate (FDR) ≤ 0.05] and downregulated (left; log₂FC ≤ 1; FDR ≤ 0.05) in each cell type. (B) Interaction network for proteins (STRING) represented by genes differentially expressed after HTT inactivation in dSPN. Red circles indicate downregulated genes and green circles indicate upregulated genes. rRNA, ribosomal RNA; srpRNA, signal recognition particle RNA; tRNA, transfer RNA.