Efficacy outcomes in patients with r/mCC treated 1L with TV + pembrolizumab in the dose-expansion arm E. (A) Waterfall plot showing the maximum percentage change in target lesions. The dashed line indicates a 30% reduction from baseline. (B) Kaplan-Meier–estimated duration of response among the 13 patients with confirmed responses. (C) Kaplan-Meier–estimated overall survival. At data cutoff (June 20, 2022), the median follow-up was 21.7 months (range, 1-29). 1L, first-line; NR, not reached; OS, overall survival; r/mCC, recurrent or metastatic cervical cancer; TV, tisotumab vedotin.