Efficacy outcomes in patients with r/mCC treated 2L or 3L with TV + pembrolizumab in the dose-expansion arm F. (A) Waterfall plot showing the maximum percentage change in target lesions. The dashed line indicates a 30% reduction from baseline. (B) Kaplan-Meier–estimated duration of response among the 12 patients with confirmed responses. (C) Kaplan-Meier–estimated overall survival. At data cutoff (June 20, 2022), the median follow-up was 15.0 months (range, 1-29). 2L, second line; 3L, third line; NR, not reached; OS, overall survival; r/mCC, recurrent or metastatic cervical cancer; TV, tisotumab vedotin.