Figure 1.

Upper panel: Timeline of the treatment course, with radiological (CT images) and clinical evidence (photos) of response. Lower panel: Histopathologic examination, at low magnification, reveals vascular neoplastic emboli in the dermis of chest skin. The tumor has a solid and cribriform architecture and enteric differentiation being positive for cytokeratin 7, CDX2, and villin. After 3 months of treatment, a new skin biopsy has been performed revealing a complete response and dermal fibrosis. CT, computed tomography.