Table 1.
Summary of demographic and clinicopathological characteristics of all the participants in this study.
| Characteristics | HC (n = 71) | Early ESCC (n = 50) | Mid-Ad ESCC (n = 50) | P value | |
|---|---|---|---|---|---|
| Demographic | |||||
| Gender | Male | 54 | 37 | 37 | |
| Female | 17 | 13 | 13 | ||
| Age (years) (mean, range) | 58 (52–63) | 60 (50–70) | 59 (50–70) | 0.09 | |
| BMI (mean, range) | 22.9 (15.2–28.7) | 22.2 (17.6–29.8) | 22 (16.4–27.3) | 0.28 | |
| Salted foods (like/dislike) | 18 (41)a | 16 (34) | 25 (25) | 0.074 | |
| Smoking (yes/no) | 31 (28)a | 30 (20) | 31 (19) | 0.568 | |
| Drinking (yes/no) | 28 (31)a | 20 (30) | 29 (21) | 0.194 | |
| Fresh vegetables and fruits (like/dislike) | 42 (17)a | 38 (12) | 34 (16) | 0.67 | |
| Family history (with/without) | 0 (59)a | 10 (40) | 6 (44) | 0.002 | |
| Hypertension (with/without) | 10 (49)a | 13 (37) | 7 (43) | 0.275 | |
| Diabetes (with/without) | 2 (57)a | 6 (44) | 5 (45) | 0.235 | |
| Clinical | |||||
| Differentiation | G0 | NA | 27 | NA | |
| G1 | NA | 16 | 20 | ||
| G2 | NA | 6 | 21 | ||
| G3 | NA | 1 | 9 | ||
| TNM stages | 0 | NA | 27 | NA | |
| IA | NA | 3 | NA | ||
| IB | NA | 20 | NA | ||
| IIA | NA | NA | 19 | ||
| IIB | NA | NA | 7 | ||
| IIIA | NA | NA | 1 | ||
| IIIB | NA | NA | 19 | ||
| IVA | NA | NA | 4 | ||
| Surgery | MATHE | NA | 12 | NA | |
| McKeown | NA | 9 | 24 | ||
| Sweet | NA | 18 | 25 | ||
| IvorLewis | NA | NA | 1 | ||
| ESD | NA | 11 | NA | ||
Patients were classified into three groups: HC, Early ESCC, and Mid-Ad ESCC.
HC healthy controls, Mid-Ad middle-advanced, ESCC esophageal squamous cell carcinoma, MATHE mediastinoscope-assisted transhiatal esophagectomy, ESD endoscopic submucosal dissection, P value in chi-square test or t test.
aThere were 12 unknown findings.