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. 2023 Dec 19;13:22641. doi: 10.1038/s41598-023-50012-8

Table 3.

Aneurysm-specific preoperative parameters, with p-values for comparing the external set to the internal set; MCA = middle cerebral artery, ACA = anterior cerebral artery, AComA = anterior communicating artery, PComA = posterior communicating artery, PCA = posterior cerebral artery, AChA = anterior choroidal artery, mRS = modified Rankin Scale, pnND = permanent new neurological deficit, GOS =  Glasgow outcome scale, tnND = transient new neurological deficit, mRS-Diff > 1 = mRS difference > 1 (preoperative vs. postoperative).

Aneurysm-specific preoperative parameters Internal Set mRS > 2 pnND GOS < 5 tnND mRS-Diff > 1 Train Set Test Set External Set p-value
Number of Aneurysms 466 59 29 63 35 48 380 86 256
Symptomatic aneurysm 41 (8.8%) 14 (23.7%) 4 (13.8%) 15 (23.8%) 6 (17.1%) 7 (14.6%) 29 (7.6%) 9 (10.5%) 74 (28.9%) < 0.0001
Calcification 31 (6.7%) 8 (13.6%) 4 (13.8%) 9 (14.3%) 3 (8.6%) 6 (12.5%) 18 (4.7%) 13 (15.1%) 67 (26.2%) < 0.0001
Aneurysm location < 0.0001
 MCA 309 (66.3%) 33 (55.9%) 12 (41.4%) 34 (54.0%) 23 (65.7%) 21 (43.8%) 255 (67.1%) 54 (62.6%) 164 (64.1%)
 ACA 29 (6.2%) 5 (8.5%) 7 (24.1%) 6 (9.5%) 1 (2.9%) 4 (8.3%) 20 (5.3%) 9 (10.5%) 5 (2%)
 AComA 116 (24.9%) 21 (35.6%) 10 (34.5%) 23 (36.5%) 10 (28.6%) 23 (47.9%) 99 (26.1%) 17 (19.8%) 61 (23.8%)
 PComA 10 (2.1%) 0 0 0 1 (2.9%) 0 5 (1.3%) 5 (5.8%) 16 (6.3%)
 AChA 2 (0.4%) 0 0 0 0 0 1 (0.3%) 1 (1.2%) 10 (3.9%)
Neck diameter; mean (range) in mm 3.9 (1–12) 4.3 (2–12) 4.1 (2–8) 4.6 (2–12) 4.7 (2–12) 4.3 (2–9) 3.9 (1–12) 3.8 (1–10) 3.0 (1–10) < 0.0001
Maximum diameter; mean (range) in mm 5.9 (1–25) 7.2 (2–25) 7.0 (3–20) 8.1 (2–25) 7.9 (3–25) 7.7 (3–21) 5.8 (1–25) 6.3 (1–21) 6.0 (1.7–25) 0.1717
Size of parenteral vessel 2.0 (1–3) 2 (1.6–3) 2 (1.7–2.3) 2.0 (1.6–3) 2.1 (1.9–3) 2.0 (2–3) 2.0 (1.1–3) 2.1 (1.7–3) 2.6 (1–6) < 0.0001
Multiple aneurysms 213 (45.7%) 26 (44.1%) 13 (44.8%) 25 (39.7%) 13 (37.1%) 18 (37.5%) 176 (46.3%) 37 (43.0%) 129 (50.4%) 0.2284
Irregular morphology / Lobulation 172 (36.9%) 30 (50.8%) 17 (58.6%) 32 (50.8%) 12 (34.3%) 27 (56.3%) 145 (38.4) 27 (31.4%) 71 (27.7%) 0.0101